KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK2
All Species:
46.06
Human Site:
T72
Identified Species:
63.33
UniProt:
P24941
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24941
NP_001789.2
298
33930
T72
K
L
L
D
V
I
H
T
E
N
K
L
Y
L
V
Chimpanzee
Pan troglodytes
XP_523720
325
36841
N92
R
L
L
D
V
V
H
N
E
R
K
L
Y
L
V
Rhesus Macaque
Macaca mulatta
XP_001113345
298
33812
T72
K
L
L
D
V
I
H
T
E
N
K
L
Y
L
V
Dog
Lupus familis
XP_856049
298
33839
T72
K
L
L
D
V
I
H
T
E
N
K
L
Y
L
V
Cat
Felis silvestris
Mouse
Mus musculus
P97377
346
38960
T72
K
L
L
D
V
I
H
T
E
N
K
L
Y
L
V
Rat
Rattus norvegicus
Q63699
298
33869
T72
K
L
L
D
V
I
H
T
E
N
K
L
Y
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
Q72
C
L
Q
D
V
L
M
Q
D
A
R
L
Y
L
I
Frog
Xenopus laevis
P23437
297
33852
T72
K
L
L
D
V
I
H
T
E
N
K
L
Y
L
V
Zebra Danio
Brachydanio rerio
NP_998571
298
34001
T72
K
L
R
D
V
I
H
T
E
N
K
L
Y
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23573
314
35870
S76
Q
L
F
D
V
V
I
S
G
N
N
L
Y
M
I
Honey Bee
Apis mellifera
XP_393450
299
34033
G72
Q
L
F
D
V
V
D
G
D
N
H
L
Y
L
V
Nematode Worm
Caenorhab. elegans
P34556
332
38277
Q90
G
L
E
A
V
I
M
Q
E
N
R
L
F
L
I
Sea Urchin
Strong. purpuratus
XP_790847
299
34142
S72
K
L
H
D
V
V
H
S
D
K
K
L
Y
L
V
Poplar Tree
Populus trichocarpa
XP_002306004
294
33768
S72
R
L
Q
D
V
V
H
S
E
K
R
L
Y
L
V
Maize
Zea mays
P23111
294
33816
S72
R
L
H
D
V
V
H
S
E
K
R
I
Y
L
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
S72
K
L
Q
D
V
V
H
S
E
K
R
L
Y
L
V
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
D80
L
Y
D
I
V
H
S
D
A
H
K
L
Y
L
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.8
99.6
98.9
N.A.
85.2
98.6
N.A.
N.A.
65.3
88.9
90.2
N.A.
62.7
69.9
56.9
75.9
Protein Similarity:
100
79.6
99.6
99.6
N.A.
85.8
99.6
N.A.
N.A.
77.8
94.9
94.9
N.A.
74.8
82.2
69.8
88.6
P-Site Identity:
100
73.3
100
100
N.A.
100
100
N.A.
N.A.
40
100
93.3
N.A.
40
53.3
46.6
66.6
P-Site Similarity:
100
86.6
100
100
N.A.
100
100
N.A.
N.A.
66.6
100
93.3
N.A.
73.3
73.3
66.6
86.6
Percent
Protein Identity:
66.4
66.7
N.A.
67.1
62.4
N.A.
Protein Similarity:
83.2
82.2
N.A.
81.5
79.1
N.A.
P-Site Identity:
60
53.3
N.A.
66.6
40
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
6
0
0
0
0
6
6
0
0
0
0
0
% A
% Cys:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
89
0
0
6
6
18
0
0
0
0
0
0
% D
% Glu:
0
0
6
0
0
0
0
0
71
0
0
0
0
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
6
0
0
% F
% Gly:
6
0
0
0
0
0
0
6
6
0
0
0
0
0
0
% G
% His:
0
0
12
0
0
6
71
0
0
6
6
0
0
0
0
% H
% Ile:
0
0
0
6
0
48
6
0
0
0
0
6
0
0
18
% I
% Lys:
53
0
0
0
0
0
0
0
0
24
59
0
0
0
0
% K
% Leu:
6
95
42
0
0
6
0
0
0
0
0
95
0
95
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
6
0
% M
% Asn:
0
0
0
0
0
0
0
6
0
59
6
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
18
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
18
0
6
0
0
0
0
0
0
6
30
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
6
30
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
100
42
0
0
0
0
0
0
0
0
83
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
0
0
0
0
0
0
0
95
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _